Support

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

You may wish to fundraise yourself, with family and friends or within your local group. Whatever the idea, be it large or small, we know you will have a great time raising vital funds for Big C.

Did you know we have 12 charity shops across Norfolk including a dedicated Craft Supplies Shop, Furniture Emporium, Bridal and a high-end fashion Boutique? We are always looking for high quality donations.

Volunteer

We are always looking for volunteers including in our Support Centres, shops and at our Fundraising events. Volunteering is a great way to spend some free time, meet new people, and gain experience.

Help us build a new Cancer Support Centre in Norwich. Support our vision to bring greater cancer care nearer to home. Donate now.

The role of the gut microbiota in breast cancer

The role of the gut microbiota in breast cancer

2017 Research Grant Award

£125,526 for a 48 month PhD project to start 1 Jan 2018 at Quadram Institute Bioscience, Norwich Research Park.

Grant Applicants:

Dr Lindsay Hall

Dr Stephen Robinson

Breast cancer (BC) is a common disease, which can be deadly. For many years, we have known that what we eat affects the risk of getting breast cancer later in life. However, in recent years there is also some evidence that the bacteria which naturally live in our gut can also have an impact on surviving breast cancer.

Antibiotic drugs can kill off some of our gut’s “good” bacteria. Some of our preliminary pre-clinical research has shown that when the diversity of bacteria in the gut is reduced by antibiotic treatment, tumours seem to grow larger and more quickly than when normal healthy levels of bacteria are present.

In the research proposed here, we aim to understand:

How gut bacteria in BC patients are affected by antibiotic treatment

How microbe changes correlate to anti-cancer immune responses and clinical readouts

How specific microbes interact with the gut and tumour using cell culture models

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Find out how Big C can support you and your family if you’ve been affected by cancer.

We can help to improve your quality of life, physical health, and mental wellbeing.

Some people take to the skies, run, jump, walk, swim and cycle whilst others make tea, bake cakes or shave heads.

What will you do to make a difference?

Two men from Norfolk who found themselves with cancer and having to travel for treatment, vowed local people would have access to the best treatment and support … and in 1980 the Big C Appeal was formed.