Support

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

You may wish to fundraise yourself, with family and friends or within your local group. Whatever the idea, be it large or small, we know you will have a great time raising vital funds for Big C.

Did you know we have 12 charity shops across Norfolk including a dedicated Craft Supplies Shop, Furniture Emporium, Bridal and a high-end fashion Boutique? We are always looking for high quality donations.

Volunteer

We are always looking for volunteers including in our Support Centres, shops and at our Fundraising events. Volunteering is a great way to spend some free time, meet new people, and gain experience.

Help us build a new Cancer Support Centre in Norwich. Support our vision to bring greater cancer care nearer to home. Donate now.

Research into the genetic causes of malignant melanoma

Research into the genetic causes of malignant melanoma

Signalling in malignant melanoma cells

£61,237 in autumn 2009 for a 1 year research project into the genetic causes of malignant melanoma by the School of Biological Sciences at UEA.

It’s well known that people with fair skin, freckles and red hair are more susceptible to skin cancer. Such people don’t produce as much melanin pigment in their skin, which protects against UV rays.  The gene responsible for the freckles, fair skin and red hair is called MC1R.  Particular variants of this gene are linked to increased risk of malignant melanoma, independently of their effects on skin colour.

This pilot project sets out to investigate whether the variant forms of MC1R “talk” to proteins on the cell surface differently from the normal version, and so stimulate the growth of melanoma cells.

This will lay the groundwork for further studies in the area of melanoma, whose incidence is increasing dramatically.

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Find out how Big C can support you and your family if you’ve been affected by cancer.

We can help to improve your quality of life, physical health, and mental wellbeing.

Some people take to the skies, run, jump, walk, swim and cycle whilst others make tea, bake cakes or shave heads.

What will you do to make a difference?

Two men from Norfolk who found themselves with cancer and having to travel for treatment, vowed local people would have access to the best treatment and support … and in 1980 the Big C Appeal was formed.