Support

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

You may wish to fundraise yourself, with family and friends or within your local group. Whatever the idea, be it large or small, we know you will have a great time raising vital funds for Big C.

Did you know we have 12 charity shops across Norfolk including a dedicated Craft Supplies Shop, Furniture Emporium, Bridal and a high-end fashion Boutique? We are always looking for high quality donations.

Volunteer

We are always looking for volunteers including in our Support Centres, shops and at our Fundraising events. Volunteering is a great way to spend some free time, meet new people, and gain experience.

Help us build a new Cancer Support Centre in Norwich. Support our vision to bring greater cancer care nearer to home. Donate now.

Research into the anti-cancer properties of chemicals found in fruit

Research into the anti-cancer properties of chemicals found in fruit

Preventing cancer of the oesophagous

£38,148 in autumn 2007 to the Institute of Food Research for a 1 year project to investigate the anti-cancer properties of chemicals found in fruit.

Adenocarcinoma is a cancer of the oesophagous that has a particularly poor prognosis.  It is widely accepted that diets rich in fruit and vegetables can help to protect against many types of cancer (including those of the oesophagus), and many of the thousands of chemicals present in fruit and vegetables are active against cancer cells.  One example is the proanthocyanidins, which are abundant in fruits and represent a significant component of the diet. Proanthocyanidins have been shown to inhibit the growth of several types of cancer cells and even cause them to commit suicide.

This project aims to understand how proanthocyanidins from apples induce this effect in oesophageal cancer cells, focusing on a particular set of proteins that play a role in regulating cell growth and division, and which are often disrupted in cancer cells.  This study will provide information into how these chemicals may affect the development of the disease, and will aid future studies into their use in cancer prevention or treatment.

Update:  Following the completion of the grant, the project was expanded by the research group, producing new insights into the anti-cancer activity of these natural chemicals.  The full results have been published in the journal Nutrition and Cancer, vol 66, pp 335-341.

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Find out how Big C can support you and your family if you’ve been affected by cancer.

We can help to improve your quality of life, physical health, and mental wellbeing.

Some people take to the skies, run, jump, walk, swim and cycle whilst others make tea, bake cakes or shave heads.

What will you do to make a difference?

Two men from Norfolk who found themselves with cancer and having to travel for treatment, vowed local people would have access to the best treatment and support … and in 1980 the Big C Appeal was formed.