Support

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

You may wish to fundraise yourself, with family and friends or within your local group. Whatever the idea, be it large or small, we know you will have a great time raising vital funds for Big C.

Did you know we have 12 charity shops across Norfolk including a dedicated Craft Supplies Shop, Furniture Emporium, Bridal and a high-end fashion Boutique? We are always looking for high quality donations.

Volunteer

We are always looking for volunteers including in our Support Centres, shops and at our Fundraising events. Volunteering is a great way to spend some free time, meet new people, and gain experience.

Help us build a new Cancer Support Centre in Norwich. Support our vision to bring greater cancer care nearer to home. Donate now.

Preventing prostate cancer progression through depleting ATP in the tumour microenvironment by dietary intervention

Preventing prostate cancer progression through depleting ATP in the tumour microenvironment by dietary intervention

2016 Research Grant Award

£119,987 for 48 months starting 1 Jan 2017 at the Institute of Food Research, Norwich.

Grant Applicants:

Prof Richard Mithen; Programme Leader

Dr Maria Traka; Senior Scientist

There is strong evidence that men who eat diets rich in cruciferous vegetables, such as broccoli, have reduced risk of aggressive prostate cancer. However, only a relatively few men eat sufficient amounts to have a significantly reduced risk.

A long-term project at the Norwich Research Park has developed special broccoli varieties with possible enhanced levels of anti-cancer activity. We have now used these novel broccoli varieties in a year-long diet study with men who have a diagnosis of low and intermediate risk of prostate cancer.

We tested prostate biopsy samples from these men after the diet study. We found that in many of them the cancer had either not progressed or had decreased, and that these changes were, unexpectedly, linked with an increase of sulphate and decrease of ATP – which is the main energy source in human tissue and is important for cancer cells to grow.

In the proposed project we wish to understand how broccoli causes these changes. This new understanding will help us improve our broccoli varieties and give more information on how often and in which way our special broccoli should be eaten to boost cancer protective benefits.

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Find out how Big C can support you and your family if you’ve been affected by cancer.

We can help to improve your quality of life, physical health, and mental wellbeing.

Some people take to the skies, run, jump, walk, swim and cycle whilst others make tea, bake cakes or shave heads.

What will you do to make a difference?

Two men from Norfolk who found themselves with cancer and having to travel for treatment, vowed local people would have access to the best treatment and support … and in 1980 the Big C Appeal was formed.