Support

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

You may wish to fundraise yourself, with family and friends or within your local group. Whatever the idea, be it large or small, we know you will have a great time raising vital funds for Big C.

Did you know we have 12 charity shops across Norfolk including a dedicated Craft Supplies Shop, Furniture Emporium, Bridal and a high-end fashion Boutique? We are always looking for high quality donations.

Volunteer

We are always looking for volunteers including in our Support Centres, shops and at our Fundraising events. Volunteering is a great way to spend some free time, meet new people, and gain experience.

Help us build a new Cancer Support Centre in Norwich. Support our vision to bring greater cancer care nearer to home. Donate now.

Oesophageal cancer

Oesophageal cancer

AMPK in cancer of the oesophagous

£35,346 in autumn 2007 to the School of Medicine, Health Policy and Practise at UEA for a 1 year project to investigate oesophageal cancer.

Previous studies on oesophageal cancer cells grown in the laboratory have shown that an enzyme called AMPK can stop the cells growing.  The details of how this works are not known but activating AMPK might be an important new way to treat and prevent this cancer.

This project will examine the activity of AMPK in healthy, cancerous, and pre-cancerous oesophageal cells, using compounds that activate or inhibit AMPK to work out how it controls cancer cells.  It is hoped that this will give a better understanding of what makes these cells grow and survive and will indicate whether AMPK is a good target for drug development.

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Find out how Big C can support you and your family if you’ve been affected by cancer.

We can help to improve your quality of life, physical health, and mental wellbeing.

Some people take to the skies, run, jump, walk, swim and cycle whilst others make tea, bake cakes or shave heads.

What will you do to make a difference?

Two men from Norfolk who found themselves with cancer and having to travel for treatment, vowed local people would have access to the best treatment and support … and in 1980 the Big C Appeal was formed.