Targeted therapy using nanomedicine
£47,595 in spring 2008 to the School of Chemical Sciences at the University of East Anglia for research into new types of cancer medicines.
Nanoparticles are tiny particles about 1/30,000th the thickness of a human hair. These particles can be used to deliver medicines into the body.
This project aims to coat gold nanoparticles with two key components. The first is an antibody (a biological molecule) which will target and bind to cancer cells. The second component is a light-activated drug. The combination of the antibody and drug on the gold nanoparticle will enable targeted therapy of cancer cells – leaving healthy cells unharmed.
The concept will be tested using breast cancer cells as well as blood vessel cells that are essential for the growth of solid tumours. This represents a new collaboration bringing together the skills of a chemist and a cancer specialist at the University of East Anglia to develop this novel “nanomedicine” for cancer therapy.