Support

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

Telephone Support Line 0800 092 7640

Available Monday to Friday 9.00am-5.00pm

You may wish to fundraise yourself, with family and friends or within your local group. Whatever the idea, be it large or small, we know you will have a great time raising vital funds for Big C.

Did you know we have 12 charity shops across Norfolk including a dedicated Craft Supplies Shop, Furniture Emporium, Bridal and a high-end fashion Boutique? We are always looking for high quality donations.

Volunteer

We are always looking for volunteers including in our Support Centres, shops and at our Fundraising events. Volunteering is a great way to spend some free time, meet new people, and gain experience.

Help us build a new Cancer Support Centre in Norwich. Support our vision to bring greater cancer care nearer to home. Donate now.

Influence of maspin on prostate cancer cells

Influence of maspin on prostate cancer cells

Investigation into the impact of a tumour suppressor on prostate cancer cells.

£48,787 in autumn 2007 to the School of Biological Sciences at UEA to investigate the impact of a tumour suppressor on prostate cancer cells.

A greater understanding of how cancer cells behave will allow development of targeted therapies.  One potential target is a protein called maspin which is known to be a tumour suppressor that influences the cell functions involved in the spread of cancer to new areas of the body.

This study continues existing work to study the impact of maspin in prostate cancer and combines it with a new approach.  Firstly the project aims to determine which part(s) of maspin are critical for its biological functions.  Secondly it will address how the production of maspin comes to be “switched off” in prostate cancer.  Both of these approaches will provide insights that could lead to novel prostate cancer therapies.

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Find out how Big C can support you and your family if you’ve been affected by cancer.

We can help to improve your quality of life, physical health, and mental wellbeing.

Some people take to the skies, run, jump, walk, swim and cycle whilst others make tea, bake cakes or shave heads.

What will you do to make a difference?

Two men from Norfolk who found themselves with cancer and having to travel for treatment, vowed local people would have access to the best treatment and support … and in 1980 the Big C Appeal was formed.