Drug resistance

The fight against resistant cancer cells

Spring 2010

£51,536 for a UEA School of Pharmacy research project into chemicals that help cancer cells evade therapies.

Acute myeloid leukaemia (AML) affects around 2,700 people per year and is most common in people over 50.1

Two chemicals NF-κB and Nrf2 have been found that may be factors in protecting cancer cells from being eradicated by modern chemotherapeutic drugs.

With long term survival rate from AML low and current treatment toxic to adults and children, knowing how these chemicals protect cancer cells may lead to better targeted therapeutic interventions.

To see another Nrf2 project funded by Big C, click here.

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1Data from NHS