Research into the regulation of epithelial cell function

Cell-regulating enzyme research

Spring 2010

£69,619 for a three year UEA School of Biological Sciences research project into the regulation of epithelial cell function.

The majority of common cancers such as breast, prostate, lung and colon develop from cells that form the lining between the tissues of these organs; these are known as epithelial cells.

An enzyme known as matriptase is found at a high level in many of these cancers.

This project will look at the role of matriptase in normal and cancerous cells using cells grown in culture.

A better understanding will help to determine whether matriptase is a suitable target for the development of anti-cancer therapies in the future.

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