Cell migration

Using chemical genetics to understand cell movement

Spring 2007

£52,323 to the School of Biological Sciences at UEA for a project to investigate chemicals that inhibit cell movement.
The ability for a cell to move is necessary for many functions in the body including wound healing and inflammation.  However, at times the ability for a cell to move or migrate is detrimental, as in the case of cancer cell migration which leads to secondary tumours forming away from the original cancer.  This process is called metastasis and causes a greatly diminished life expectancy when it occurs.  

Experiments have identified a number of compounds which inhibit cell migration in pigment cells and this project will determine if these compounds could be of use in inhibiting cancer cell migration.  If these compounds do have an affect then they can be investigated as targets for potential anti-cancer drugs.


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