Other Research

Big C has funded numerous projects over the years that have allowed significant strides in the diagnosis, prevention and treatment of cancer.

Below are some of the most recent projects the Big C has funded at the University of East Anglia and the Institute of Food Research.

2007 Projects
Genetic conflits and the development of cancer	£43,314
Hepson as a prostate cancer biomarker	£48,983
Purchase of TaqMan Real Time machine	£36,000
Using chemical genetics to understand cell migration	£52,323
Physico chemical studies of IDO, a potential target for anti cancer therapeutics	£40,356
Maspin in prostate cancer the regulation and mechanism of action of this non-inhibitory serpin (1year)	£48,787
Identifying substrates for the cancer associated enzyme MMP-28 (1 year)	£51,298
Regulation of MMP-28 - a gene associated with metastasis in head and neck cancers (1 year)	£51,017

Anti cancer effects of 5' AMP-kinase in Barrett's oesophagus and oesophageal adenocarcinoma (1year)

£35,346

Previous Projects
Non-homologous End-joining of DNA in bacteria	£38,993
Role of transmembrane serine proteases in the regulation of HGF/scatter factor activity in prostate cancer	£38,808
New Perspectives in Cancer Diagnosis, Treatment and Prevention	£4,500
Provision of a multi-user LAS3000 image analyser	£23,000
The identity of specific histone deacetylases impacting on Timp-1gene expression	£34,617
What stops human cancer cells from moving? Exploring the role of the tumour suppressor gene, vhl.	£30,000
The role of the Adenomatous Polyposis Coli protein in the generation and maintenance of apicp-basal microtube arrays in polarised epithelial cells	£38,046
How do inappropriate Wnt/?-catenin signals initiate colorectal cancer?	£34,993

Research is a continuing process that needs continuing support. If you would like to discuss our research further or would like to donate to our research programme please contact us